Chelsea are good value to win at Sunderland for the sixth consecutive season, with midfielder Frank Lampard netting in a 2-1 victory.
Stoke have only let in three goals in six home games and can get back on track with a 2-0 win over Cardiff, Peter Crouch scoring first.
Fulham, despite a change in boss, look there for the taking and Tottenham get the nod to prevail 2-1, Roberto Soldado finding the net.
Norwich have lost five of six away games so go with Liverpool to triumph 2-0 and Luis Suarez the obvious pick to break the deadlock.
Hull have struggled away and Arsenal are expected to stay ahead of the chasing pack with a 3-0 win, with Olivier Giroud to score first.
Swansea did the double over Newcastle last term but the visitors have improved so expect a 1-1 draw, with Jonjo Shelvey netting first.
Manchester City need to improve their results on the road and are fancied to beat West Brom 3-1 with Samir Nasri finding the net first.
Southampton are looking to bounce back against Aston Villa, with England striker Rickie Lambert fancied to fire his side to a 2-0 win.
David Moyes will be determined to put one over his ex-club Everton, with Manchester United taken to prevail 3-1 and Nani scoring first.