Swansea are fancied to shade a QPR outfit lacking in attacking flair, with Michu worth backing to break the deadlock in a 1-0 home win.
Arsenal can repeat last season's 2-1 success at Sunderland, while striker Lukas Podolski is a safe bet for the first goalscorer.
Stoke are worth sticking with to get back on track with a 2-1 triumph over Reading, while Peter Crouch is a decent bet for first goal.
Manchester City can get back to winning ways and shade their clash at Southampton 2-1, with hot-shot SergioAguero tipped to net first.
A 1-1 draw could be on the cards between Norwich and Fulham, with midfielder Wes Hoolahan taken to break the deadlock for the Canaries.
Chelsea have too many weapons up front and are fancied to prevail 3-1against Wigan, with Fernando Torres opening the scoring.
Man City are hard to oppose at home but Liverpool should run them close. Back the hosts to prevail 2-1 with Sergio Aguero to net first.
Three of the last five meetings between West Brom and Tottenham ended in stalemate so Gareth Bale should open the scoring in 1-1 draw.
Wigan and Southampton will provide an entertaining 2-2 draw and hedge those bets by siding with Di Santo to strike first for the hosts.