Villa striker Christian Benteke can prove too hot to handle for Reading, so back the him to break the deadlock in a 2-1 away win.
QPR may just be hungrier for success than Sunderland and striker Loic Remy can be the difference a 1-0 home victory at Loftus Road.
Rickie Lambert is worth backing to strike first for Saints in 1-1draw at Norwich after netting in six of his last seven away matches..
Man City should prove too strong for Aston Villa, with 3-1 the chosen scoreline and Sergio Aguero the most likely man to score first.
Arsenal have toiled at White Hart Lane so back Tottenham to win 2-1 with Emmanuel Adebayor to net the opener against his former club.
Take Wigan to battle for a point against Liverpool, although hedge those bets by backing Luis Suarez to score first in a 1-1 stalemate.
Take Newcastle to secure a 1-1 draw at Swansea, with Papiss Cisse capable of building on his spectacular strike versus Southampton.
Stoke are the percentage pick against West Ham and striker Jonathan Walters can break the deadlock in a 2-1 victory. at the Brittania.
Striker Steven Fletcher is fancied to secure a low-scoring 1-0 success for the Black Cats when Fulham visit the Stadium of Light.